Last edited by Bratilar
Thursday, July 16, 2020 | History

5 edition of Neoplastic transformation in human cell culture found in the catalog.

Neoplastic transformation in human cell culture

mechanisms of carcinogenesis

  • 256 Want to read
  • 8 Currently reading

Published by Humana Press in Totowa, N.J .
Written in English

    Subjects:
  • Carcinogenesis -- Congresses,
  • Cell transformation -- Congresses,
  • Human cell culture -- Congresses,
  • Cell Transformation, Neoplastic -- congresses,
  • Cells Cultured -- congresses

  • Edition Notes

    Statementedited by Johng S. Rhim, Anatoly Dritschilo.
    SeriesExperimental biology and medicine, Experimental biology and medicine (Clifton, N.J.)
    ContributionsRhim, Johng S., Dritschilo, Anatoly., Georgetown University. Dept. of Radiation Medicine., University of Chicago. Dept. of Radiation and Cellular Oncology.
    Classifications
    LC ClassificationsRC268.5 .N46 1991
    The Physical Object
    Paginationxxxi, 396 p. :
    Number of Pages396
    ID Numbers
    Open LibraryOL1555153M
    ISBN 100896032272
    LC Control Number91035328

    The development of biology in this century has proceeded from the organismic level to the molecular level. Retrovirology has followed this broad historical trend. In the first six decades of the century, retrovirology dealt almost exclusively with infection and disease in the animal host. This was followed in the s and s by a dominant concern with the viral replication cycle and Author: John M Coffin, Stephen H Hughes, Harold E Varmus.   HEp-2 (Human larynx epidermal carcinoma, BSTCL 23) and MRC-5 cells (Human foetal lung, BSCL 68) (both from the IZSLER biobank), were grown in MEM culture medium supplemented with 10% FBS and 2 mM l-glutamine. These cell lines were used respectively as positive and negative control in tumorigenicity and transformation : N. A. Andreani, S. Renzi, G. Piovani, P. Ajmone Marsan, L. Bomba, R. Villa, M. Ferrari, S. Dotti.

    The book is divided into four sections: human cell. The importance of the system for the diagnosis of metabolic disease forthe study of immune response neoplastic trans- tissue-culture formation are clearly presented documented. Cell culture models of oncogenesis that use cellular reprogramming to generate a neoplastic cell from a normal cell provide one of the few opportunities to study the early stages of breast cancer development. Human mammary epithelial cells (HMECs) were induced to undergo a neoplastic transformation using defined genetic elements to generate transformed HMECs (THMECs).Cited by:

    Nickel is a well-known human lung carcinogen with the particulate form being the most potent; however, the carcinogenic mechanism remains largely unknown. Few studies have investigated the genotoxicity and carcinogenicity of nickel in its target cell, human bronchial epithelial cells. Thus, the goal of this study was to investigate the effects of particulate nickel in human lung epithelial : Amie L. Holmes, Kelsey Thompson, Michael Mason, Sanjeev Kandpal, Tongzhang Zheng, John Pierce Wise. A book of the names and address of people living in a city What is neoplastic cancer Intracellular Signaling Peptides and Proteins, Cancer cells, Cancer, Neoplastic Cell Transformation.


Share this book
You might also like
Levellers levelled, or, The Independents conspiracie to root out Monarchie

Levellers levelled, or, The Independents conspiracie to root out Monarchie

River out of Eden.

River out of Eden.

Rebirthing Made Easy

Rebirthing Made Easy

Riley farm-rhymes

Riley farm-rhymes

Analysis and reactions of cyclopropenoids with rhodium complexes.

Analysis and reactions of cyclopropenoids with rhodium complexes.

KOREA INDUSTRIAL DEVELOPMENT CO., LTD.

KOREA INDUSTRIAL DEVELOPMENT CO., LTD.

My Child Is Not Missing

My Child Is Not Missing

BAYERISCHE BRAUHOLDING AG

BAYERISCHE BRAUHOLDING AG

Literary criticism in the age of Johnson.

Literary criticism in the age of Johnson.

Management and men

Management and men

Think with the senses, feel with the mind : art in the present time. (52. Ezposisione Internazionale dArte la Biennale di Venezia).

Think with the senses, feel with the mind : art in the present time. (52. Ezposisione Internazionale dArte la Biennale di Venezia).

Red Grooms, Michael C. McMillen: A collaboration

Red Grooms, Michael C. McMillen: A collaboration

Neoplastic transformation in human cell culture Download PDF EPUB FB2

The role of carcinogenic agents in the deveolopment of human cancers is now being defined using a variety of human cells as experi­ mental model systems. A workshop on "neoplastic transformation in human cell systems in vitro: mechanisms of carcinogenesis" was held at the Georgetown University Medical Center, Washington, DC, on April A workshop on "neoplastic transformation in human cell systems in vitro: mechanisms of carcinogenesis" was held at the Georgetown University Medical Center, Washington, DC, on AprilThe aims of the workshop were to present the state-of-the­ art in the transformation of human cells in culture, as well as to provide insight into the Format: Paperback.

Neoplastic Transformation in Human Cell Culture by Johng S. Rhim,available at Book Depository with free delivery worldwide. Get this from a library. Neoplastic transformation in human cell culture: mechanisms of carcinogenesis.

[Johng S Rhim; Anatoly Dritschilo; Georgetown University. Department of Radiation Medicine.; University of Chicago. Department of Radiation and Cellular Oncology.;] -- "Rhim and Dritschilo's state-of-the-art volume on Neoplastic Transformation in Human Cell Culture highlights the latest.

Comparison of human versus rodent cell transformation: importance of cell aging.- Deficient DNA repair, an early step in neoplastic transformation of human cells in culture.- Use of immortalized human keratinocytes for the study of squamous differentiation and mutagenesis.-Price: $ Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells.

The process is characterized by changes at the cellular, genetic, and epigenetic levels and abnormal cell division is a physiological process that occurs in almost all tissues and under a variety of circumstances. Get this from a library.

Neoplastic Transformation in Human Cell Culture: Mechanisms of Carcinogenesis. [Johng S Rhim; Anatoly Dritschilo]. A neoplasm (/ ˈ n iː oʊ p l æ z əm, ˈ n i ə-/) is a type of abnormal and excessive growth, called neoplasia, of growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and it persists growing abnormally, even if the original trigger is lty: Oncology.

Lehman T.A., Harris C.C. () Neoplastic Transformation and Suppression of Transformation of Human Bronchial Epithelial Cells in vitro. In: Rhim J.S., Dritschilo A. (eds) Neoplastic Transformation in Human Cell : Teresa A.

Lehman, Curtis C. Harris. Read here ?book=[PDF] Neoplastic Transformation in Human Cell Culture: Mechanisms of Carcinogenesis Download. This book, part contributed volume, part proceedings, discusses state-of-the-art advances on human cell transformation in cell models for the study of cancer and aging.

Several of the chapters are from the Human Cell Transformation: Advances in Cell Models for the Study of Cancer and Aging conference that was held in June at McGill University. @article{osti_, title = {Enhanced G2 chromatid radiosensitivity, an early stage in the neoplastic transformation of human epidermal keratinocytes in culture}, author = {Gantt, R and Sanford, K K and Parshad, R and Price, F M and Peterson, Jr, W D and Rhim, J S}, abstractNote = {A deficiency in DNA repair, manifest as enhanced chromatid radiosensitivity during the G2 phase of the cell Author: Gantt, R.

Cell transformation is a complex process that often results in the formation of neoplastic cells. The cell lines obtained from malignant tumors are already transformed.

Such cells may undergo further transformation in the in vitro culture due to: i. Increased growth rate. Immortalization. iii. Reduced anchorage dependence. For the malignant. Background Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are in the foreground as a preferable application for treating diseases.

However, the safety of hUC-MSCs after long-term culturing in vitro in serum-free medium remains unclear. Methods hUC-MSCs were separated by adherent tissue culture. hUC-MSCs were cultured in serum-free MesenCult-XF medium and FBS. neoplastic transformation in rodent cells (18, 20, 21); however, only a few studies considered human cell models and none have considered human bronchial cells (37, 38).

Neoplastic transformation of human lung fibroblast MRC-5 SV2 cells induced by benzo[a]pyrene and confluence culture Article (PDF Available) in Cancer Research 62(16) September with.

The Human Ads—Model Systems to Understand Virus Replication, Human Cell Molecular Biology, and Neoplastic Transformation The human Ads provide some of the best experimental systems for investigating oncogenic DNA-virus replication, cell transformation, and the molecular biology of human and transformed cells.

The Ads replicate in the nucleus. Given the duration of aging in humans, cell culture studies are a promising approach to the study of human aging, based on the assumption that human aging has, at least in part, a cellular origin (Magalhães, ). There is little evidence, however, that cellular senescence is a significant factor in human aging or that the mechanisms.

The following chapters focus on microbial and mammalian mutagenesis by PAHs; mechanisms of DNA excision repair in human cells; effect of DNA repair on the cytotoxicity and mutagenicity of PAH metabolites in human cells; and oncogenic transformation of cell cultures by PAHs and their derivatives.

These processes demand strict interregulation of cell replication and squamous and mucoepidermoid differentiation control mechanisms. Aberrations in these processes positively correlate with a high risk for neoplastic transformation.

Replicative cultures of normal human bronchial epithelial (NHBE) cells offer opportunities to study these by: 7. cell transformation, neoplastic () Filter by: Remove filter: male () Filter by: Remove filter: cell biology () Filter by: Remove filter: expression () Filter by: Remove filter: gene expression regulation, neoplastic () Filter by.This report describes the in vitro neoplastic transformation of a normal human mammary epithelial cell strain, 76N, by fractionated [gamma]-irradiation at a clinically used dose (30 Gy).

The transformed cells (76R) were immortal, had reduced growth factor requirements, and produced tumors in nude mice.Human Esophageal Epithelial Cells: Immortalization and In Vitro Transformation.

G.D. Stoner, Z. Naito, and G.E. Milo. Transformation of Human Endometrial Stromal Cells In Vitro. C.A. Rinehart et al. Factors Influencing Growth and Differentiation of Normal and Transformed Human Mammary Epithelial Cells in Culture. M.R. Stampfer and P. Yaswen.